Sympathomimetic amine; induces anorectic effect via release of norepinephrine in the hypothalamus causing appetite suppression by increasing blood leptin concentration; exact mechanism of action unknown. Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Indication Qsymia should be used together with a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index BMI of: Sufficient calories and nutrition are important for proper lactation.
Blood glucose monitoring is warranted in patients with type 2 diabetes prior to starting and during phentermine; topiramate treatment. In those with severe bleeding events, patients were often taking drugs that cause thrombocytopenia or affect platelet function or coagulation. People who stayed on Qsymia lost an average of 25 pounds Depending on dose.
Caffeine should be avoided or used cautiously with phentermine. Topiramate is a weak CYP3A4 inducer. Only available through certified pharmacies enrolled in Qsymia certified pharmacy network.
Am J Clin Nutr. The benefit of this weight loss is not known. Your healthcare provider should check your heart rate while you take Qsymia. Major Due to the potential for increases in blood pressure and heart rate, atomoxetine should be used cautiously with drugs with sympathomimetic activity such as phentermine. Major Phentermine, which increases catecholamine release, can increase blood pressure; this effect may be additive with the prolonged vasoconstriction caused by ergot alkaloids.
Moderate Maprotiline, when used concomitantly with anticonvulsants, can increase CNS depression and may also lower the seizure threshold, leading to pharmacodynamic interactions. Administration of ivacaftor with strong CYP3A inducers is not recommended because sub-therapeutic ivacaftor exposure could result; the impact of mild inducers is not known.
The concomitant use of topiramate with other carbonic anhydrase inhibitors or in patients on a ketogenic diet may create a physiological environment that increases the risk of kidney stone formation, and should therefore be avoided.
Take Qsymia with a reduced calorie diet and increased activity
Additive CNS stimulant effects are likely to occur when caffeine is coadministered with other CNS stimulants or psychostimulants. Patients receiving this combination should be monitored for the emergence of serotonin syndrome.
Overview Side Effects Dosage More. Some of the cases have been reported with topiramate after exposure to elevated environmental temperatures.
Moderate Sympathomimetic amines should be used with caution in patients with thyrotoxicosis since these patients are unusually responsive to sympathomimetic amines. Send the page " " to a friend, relative, colleague or yourself.