Albendazole is extensively metabolized by the liver; hepatic clearance may be impaired if hepatic disease or biliary obstruction are present and may result in increased side effects.
Your list will be saved and can be edited at any time. Patient Version Drug Information What is albendazole?
Usual Adult Dose for Hydatid Disease
In general, the following organisms are susceptible to albendazole: Albendazole may increase the clearance of the tricyclic antidepressants. Brand and Other Names: Opportunistic Infections and Coinfections. A report of 10 women exposed to accidental high doses of albendazole during the first trimester states that all women delivered normal infants and that some of the infants were followed for up to one year without incident. Average dosage is mg PO twice daily.
To view content sources and attributions, please refer to our editorial policy.
Albendazole Rating 6 User Reviews 8. In some infections, additional treatments with this medicine may be needed at 2-week intervals to clear up the infection completely.
Proper Use Drug information provided by: Contraception requirements, pregnancy testing, reproductive risk.
Before initiating therapy for neurocysticercosis, the patient should be examined for retinal lesions retinal cysticercosis. Albendazole induces cytochrome P 1A in human hepatoma cells; therefore, it is recommended that plasma concentrations of theophylline be monitored during and after treatment.
Therefore, closer monitoring of blood counts is needed in these patients. By clicking send, you acknowledge that you have permission to email the recipient with this information. Albendazole is practically insoluble in alcohol and in water. Grapefruit juice also increases albendazole's oral bioavailability. The AUC and Cmax of albendazole increased approximately 3-fold and the half-life was shortened by 46 percent when administered with grapefruit juice. However, the World Health Organization WHO supports the use of albendazole as antihelminthic therapy after the first trimester of pregnancy.
The systemic anthelmintic activity has been attributed to the primary metabolite, albendazole sulfoxide.