Tacrolimus usmle

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Prevent cardiac ischemia in unstable angina 2.

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Gastrointestinal upset Pancytopenia Hypertension Hyperglycemia. Question Comments Subscribe status: Please login to view and post comments. Suppress organ rejection after transplants 2.

Binds to cyclophilins 2. Give an example of thalidomide toxicity.

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What is it's clinical use? Magnetic resonance imaging of the brain and spine shows new enhancing lesions when compared to prior imaging. Give 2 clinical uses.

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After further evaluation it was determined she had an MS exacerbation. Drug-induced Cushing-like symptoms Hyperglycemia Osteoporosis Mood alterations. Because it accounts for 5 to 10 percent of patients with end-stage renal disease, it is also a common indication for renal transplantation. Illustration A shows the mechanism of action of sirolimus. Join now Sign in. A year-old woman presents to the emergency department with worsening weakness and decreased visual acuity of the right eye.

Give 2 clinical uses for cyclosporine. Which of the following are side effects of this medication? What is its clinical use? Upgrade to remove ads. Inosine monophosphate dehydrogenase inhibitor Cytostatic effect on lymphocytes lymphocytes do not have enzymes involved in salvage pathway, and thus why they are preferentially affected.

This differentiates it from cyclosporine which works by inhibiting calcineurin. Blocks differentiation and activation of T-cells by inhibiting calcineurin and therefore preventing production of IL-2 and its receptor. Rituximab B-cell non-Hodgkin's lymphoma. Please login to add comment.

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Rheumatoid arthritis Renal transplantation Inflammatory bowel disease. Name 4 drugs that affect IL-2 autocrine growth factor signaling and therefore affect T-cell activation. They report that metabolic toxicities, including hyperglycemia, hyperlipidemia, and hypophosphatemia, are some side effects of various mTOR inhibitors. Sirolimus, cyclosporine, and steroids are a commonly used immunosuppressive regimen in renal transplants.

Diagnosis is usually made in middle age, when complications such as hypertension, pain and hematuria develop.